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Cadherin-17

Cadherin-17 Molekülinformation

Englischer Name	Cadherin-17	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	8	Target-Alias	Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Cadherin-17
Target-Alias	Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	8
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Cadherin-17 Produktliste

Attribut
Protein (29)Cell (1)
Produktbibliothek
Online (31)
Spezies
Mouse (4)Human (22)Rat (1)Cynomolgus (3)
Etikett
His Tag (10)His Tag & Avi Tag (4)Mouse IgG Fc Tag (1)Fc Tag (12)Fc Tag & Avi Tag (2)- (2)
Marker
Unconjugated (22)Biotin-labeled (6)- (2)FITC Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CA7-H52E6	Human	HEK293	Biotinylated Human Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
HOT CA7-H52H3	Human	HEK293	Human Cadherin-17 / CDH17 Protein, His Tag	In den Warenkorb legen
HOT CA7-H52H4	Human	HEK293	Human Cadherin-17 / CDH17 Protein, His Tag, low endotoxin (Active)	In den Warenkorb legen
HOT CA7-M52H5	Mouse	HEK293	Mouse Cadherin-17 / CDH17 Protein, His Tag (MALS verified)	In den Warenkorb legen
HOT CA7-C52H3	Cynomolgus	HEK293	Cynomolgus Cadherin-17 / CDH17 Protein, His Tag (MALS verified)	In den Warenkorb legen
CA7-H5253	Human	HEK293	Human Cadherin-17 / CDH17 Protein, Fc Tag (Active, MALS verified)	In den Warenkorb legen
CA7-H5254	Human	HEK293	Human Cadherin-17 / CDH17 Protein, Fc Tag	In den Warenkorb legen
CA7-H5255	Human	HEK293	Human Cadherin-17 / CDH17 (450-566) Protein, Fc Tag (MALS verified)	In den Warenkorb legen
CA7-H5256	Human	HEK293	Human Cadherin-17 / CDH17 (341-449) Protein, Fc Tag	In den Warenkorb legen
CA7-H5257	Human	HEK293	Human Cadherin-17 / CDH17 (129-244) Protein, Fc Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge30

Cadherin-17 Molekülhintergrund

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Cadherin-17 Molekülalias

Cadherin-17,CDH17,HPT-1,LI-cadherin

Antikörperprojekt-Handelsplattform

Projektname	Projektphase	Molekültyp	Molekülquelle	Krankheitsgebiet	Indikationen
CDH17 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Colorectal cancer,Gastric Cancer

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
CHM-2101	CDH17-CAR T; CHM-2101; CHM2101; CHM-2101 CAR-T cells	Phase 2 Clinical	University Of Pennsylvania	Stomach Neoplasms; Pancreatic Neoplasms; Neuroendocrine Tumors; Colorectal Neoplasms; Gastrointestinal Neoplasms	Details
BI-905711	BI-905711	Phase 1 Clinical	Boehringer Ingelheim Gmbh	Pancreatic Neoplasms; Cholangiocarcinoma; Gastrointestinal Neoplasms	Details
Cabotamig	ARB-202	Phase 1 Clinical	Arbele Corp	Liver Neoplasms; Biliary Tract Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal adenocarcinoma; Gastrointestinal Neoplasms	Details
Anti-CDH17 CAR-T cells Therapy (Guangzhou Bio-Gene Technology)		Phase 1 Clinical	Guangzhou Bio-Gene Technology Co Ltd	Solid tumours	Details
HS-20110	HS20110; HS-20110	Phase 1 Clinical	Shanghai Hansoh Biomedical Co Ltd, Changzhou Hengbang Pharmaceutical Co Ltd	Solid tumours	Details
Anti-CDH17 CAR-T Cell therapy (UTC Therapeutics)		Phase 1 Clinical	UTC Therapeutics Inc	Solid tumours	Details
TORL-3-600	TORL-3-600	Phase 1 Clinical	Torl Biotherapeutics LLC	Solid tumours; Colorectal Neoplasms	Details
CDH17 - IHC Test(Arbele)		Clinical	Arbele Corp	Gastrointestinal Neoplasms	Details

Produktrezensionen

T***I2025-11-07
0Menschen mögen
Cynomolgus Cadherin-17 / CDH17 Protein, His Tag (MALS verified)
This time purchased 100ug human protein FG9-H51H3, used for validation experiments. The experimental bands are clear, antigen-antibody binding effect is good, overall experience is good, will repurchase.

Molekülinformation
Produktliste
Produktrezensionen
Klinische Arzneimittelinformation

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