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NOTCH3

NOTCH3 Molekülinformation

Englischer NameNeurogenic locus notch homolog protein 3Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0Target-AliasNeurogenic Locus Notch Homolog Protein 3,LMNS,Notch 3,NOTCH3,Notch (Drosophila) Homolog 3,Notch Homolog 3 (Drosophila),Notch Homolog 3,CADASIL1,CADASIL,CASIL,IMF2,Receptor, Notch3,Notch Receptor 3
Höchste Forschungs- und EntwicklungsphasePreclinical
Englischer NameNeurogenic locus notch homolog protein 3
Target-AliasNeurogenic Locus Notch Homolog Protein 3,LMNS,Notch 3,NOTCH3,Notch (Drosophila) Homolog 3,Notch Homolog 3 (Drosophila),Notch Homolog 3,CADASIL1,CADASIL,CASIL,IMF2,Receptor, Notch3,Notch Receptor 3
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePreclinical

NOTCH3 Produktliste

  • Attribut

    Protein (1)

  • Produktbibliothek

    Online (1)

  • Spezies

    Human (1)

  • Etikett

    Fc Tag (1)

  • Marker

    Unconjugated (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
NO3-H5255
Human
HEK293
Human NOTCH3 Protein, Fc Tag
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Gesamtmenge1
  • 1

NOTCH3 Molekülhintergrund

Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs

NOTCH3 Molekülalias

Notch-3,NOTCH3
  • Molekülinformation
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