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LIF

LIF Molekülinformation

Englischer NameLeukemia inhibitory factorAnzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel2Target-AliasLIF Interleukin 6 Family Cytokine，D factor，Emfilermin，LIF，Differentiation-stimulating factor，LIF， Interleukin 6 Family Cytokine，Differentiation Inhibitory Activity，Cholinergic Differentiation Factor，Hepatocyte-Stimulating Factor III，Differentiation-Inducing Factor，Melanoma-Derived LPL Inhibitor，Human Interleukin In DA Cells，Leukemia Inhibitory Factor，HILDA，MLPLI，CDF，DIA
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Englischer NameLeukemia inhibitory factor
Target-AliasLIF Interleukin 6 Family Cytokine，D factor，Emfilermin，LIF，Differentiation-stimulating factor，LIF， Interleukin 6 Family Cytokine，Differentiation Inhibitory Activity，Cholinergic Differentiation Factor，Hepatocyte-Stimulating Factor III，Differentiation-Inducing Factor，Melanoma-Derived LPL Inhibitor，Human Interleukin In DA Cells，Leukemia Inhibitory Factor，HILDA，MLPLI，CDF，DIA
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel2
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical

LIF Produktliste

  • Attribut

    Protein (6)

  • Produktbibliothek

    Online (6)

  • Spezies

    Human (4)Mouse (2)

  • Etikett

    Tag Free (3)His Tag (2)His Tag & Avi Tag (1)

  • Marker

    Unconjugated (5)Biotin-labeled (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
HOT
LIF-H521b
Human
HEK293
Human LIF Protein, Tag Free
 In den Warenkorb legen
HOT
LIF-H52H3
Human
HEK293
Human LIF Protein, His Tag (MALS verified)
 In den Warenkorb legen
HOT
LIF-H82E2
Human
HEK293
Biotinylated Human LIF Protein, His,Avitag™
 In den Warenkorb legen
LIF-H5215
Human
HEK293
Human LIF Protein, premium grade
 In den Warenkorb legen
LIF-M5219
Mouse
HEK293
Mouse LIF Protein, Tag Free (MALS verified)
 In den Warenkorb legen
LIF-M5227
Mouse
HEK293
Mouse LIF Protein, His Tag (MALS verified)
 In den Warenkorb legen
Gesamtmenge6
  • 1

LIF Molekülhintergrund

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

LIF Molekülalias

LIF,CDF,DIA,HILDA,MLPLI

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
FalbikitugAZD-0171; MSC-1Phase 2 ClinicalAstrazeneca PlcSolid tumours; Ovarian Neoplasms; Pancreatic Neoplasms; Carcinoma, Non-Small-Cell Lung
Details
JAB-BX300JAB-BX300Phase 1 ClinicalJacobio Pharmaceuticals Co LtdSolid tumours; Pancreatic Neoplasms
Details
  • Molekülinformation
  • Produktliste
  • Klinische Arzneimittelinformation
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