Select Language

IgG3 Fc

IgG3 Fc Overview

English Name	Immunoglobulin G	Approved Drugs	1
Drugs in Clinical Trials	6	Target Synonym	Immunoglobulin G
Highest Development Stage	Approved

English Name	Immunoglobulin G
Target Synonym	Immunoglobulin G
Approved Drugs	1
Drugs in Clinical Trials	6
Highest Development Stage	Approved

IgG3 Fc Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (2)Mouse (1)
Tag
Tag Free (2)Avi Tag (1)
Conjugate
Unconjugated (2)Biotin-labeled (1)

Cat. No.	Species	Host	Product Description
IG3-H5200	Human	HEK293	Human IgG3 Fc Protein, Tag Free (MALS & SPR verified)
IG3-H8213	Human	HEK293	Biotinylated Human IgG3 Fc Protein, Avitag™ (MALS verified)
IG3-M5214	Mouse	HEK293	Mouse IgG3 Fc Protein, Tag Free (MALS verified)

Total: 3

IgG3 Fc Background

Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3).

IgG3 Fc Synonyms

Ig gamma-3 chain C region,IgG,IgG3

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Ricefidase	KJ-103; KJ103	Phase 3 Clinical	Shanghai Bao Pharmaceuticals Co Ltd	Rejection of renal transplantation; Anti-Glomerular Basement Membrane Disease	Details
AT-02	AT-02	Phase 2 Clinical	Attralus Inc	Immunoglobulin Light-chain Amyloidosis; Amyloidosis	Details
S-1117	S-1117	Phase 1 Clinical	Seismic Therapeutics Inc	Immune System Diseases	Details
BHV-1300	BHV-1300	Phase 1 Clinical	Biohaven Pharmaceuticals Inc	Arthritis, Rheumatoid	Details
HNSA-5487	HNSA 5487; HNSA-5487	Phase 1 Clinical	Hansa Biopharma Ab	Neoplasms; Autoimmune Diseases	Details
Anti-CD33/anti-FcgammaRI bispecific antibody (UCSD)		Phase 1 Clinical	University Of California San Diego	Leukemia, Myeloid, Acute	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Imlifidase	Mac-1	Approved	Hansamed Inc	Idefirix	EU	Rejection of renal transplantation	Hansa Biopharma Ab	2020-08-25	Rejection of renal transplantation; Kidney Diseases; Purpura, Thrombotic Thrombocytopenic; Rejection of organ transplantation; Renal Insufficiency, Chronic; Guillain-Barre Syndrome; Kidney Failure, Chronic	Details