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IgG1 Fc

IgG1 Fc Product List

Product Category
Protein (16)
Product Status
Launched (16)
Species
Human (14)Mouse (2)
Tag
Tag Free (3)His Tag (8)Avi Tag (2)gD Tag (1)Flag Tag (1)His Tag & Avi Tag (1)
Conjugate
Unconjugated (11)Biotin-labeled (3)FITC Labeled (1)Cy5 Labeled (1)

Cat. No.	Species	Host	Product Description
HOT FCC-H5214	Human	HEK293	Human IgG1 Fc Protein, Tag Free (MALS verified)
HOT IG1-H5225	Human	HEK293	Human IgG1 Fc Protein, His Tag (MALS verified)
HOT IG1-H52C9	Human	HEK293	Human IgG1 Fc (C103S) Protein, Flag Tag (MALS verified)
HOT IG1-H8213	Human	HEK293	Biotinylated Human IgG1 Fc protein, Avitag™ (MALS & SPR verified)
HOT IG1-H82E9	Human	HEK293	Biotinylated Human IgG1 Fc (C103S) Protein, Avitag™,His Tag (HPLC verified)
IG1-H52G6	Human	HEK293	Human IgG1 Fc (C103S) Protein, gD Tag (MALS verified)
IG1-H52H1	Human	HEK293	Human IgG1 Fc (C103S, D239E, L241E) Protein, Tag Free (MALS verified)
IG1-H52H5	Human	HEK293	Human IgG1 Fc (C103S, M135Y, S137T, T139E) Protein, His Tag (MALS verified)
IG1-H52H6	Human	HEK293	Human IgG1 Fc (C103S, L117A, L118A) Protein, His Tag
IG1-H52H7	Human	HEK293	Human IgG1 Fc (C103S, N180A) Protein, His Tag (MALS verified)

Total: 16

IgG1 Fc Background

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Product Reviews

Y***g2025-05-10
1People Like
Human IgG1 Fc (C103S) Protein, Flag Tag (MALS verified)
Always high-quality products — they worked well in my experiments with excellent batch-to-batch consistency.
R***s2022-07-30
0People Like
Human IgG1 Fc (C103S, L117F, L118E, P214S) Protein, His Tag (MALS verified)
Used this reagent for a discovery campaign. This product arrived on time and after testing it with our own internal methods, we concluded that it was high quality material. We had no problems using it for our experiments and it lasted a long time without a decrease in quality. We will definitely be ordering from here again after this great experience. Thanks!
D***z2021-09-02
1People Like
Human IgG1 Fc Protein, Tag Free (MALS verified)
Worked well in a sandwich ELISA; was being used to compare reagents to determine which component of a previously functional assay was failing. Reconstitution instructions and handling directions were straightforward, and produced a reagent of good concentration and volume. Good value, and intuitive storage conditions. The only criticism I have is that the solubilization step seems like it's a bit too long, but instructions were followed as given in the CofA and product worked well. Can't complain!