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BMP-2

BMP-2 Overview

English Name	Bone morphogenetic protein 2	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	Bone Morphogenetic Protein 2，BMP-2，Bone morphogenetic protein 2A，BDA2，SSFSC，BMP-2A，BMP2A
Highest Development Stage	Phase 1 Clinical

English Name	Bone morphogenetic protein 2
Target Synonym	Bone Morphogenetic Protein 2，BMP-2，Bone morphogenetic protein 2A，BDA2，SSFSC，BMP-2A，BMP2A
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 1 Clinical

BMP-2 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
Tag Free (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
BM2-H4117	Human	E. coli	Human BMP-2 Protein, premium grade

Total: 1

BMP-2 Background

Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.